Two sample MR report
LILRA2_Monocyte (Mono) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.1371283 | 0.1217906 | 0.3113141 |
| Weighted median | 7 | 0.0531391 | 0.0192905 | 0.0058750 |
| Inverse variance weighted | 7 | 0.0398014 | 0.0138957 | 0.0041793 |
| Simple mode | 7 | 0.0600190 | 0.0278603 | 0.0746637 |
| Weighted mode | 7 | 0.0591119 | 0.0266866 | 0.0686656 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.660513 | 5 | 0.7521508 |
| Inverse variance weighted | 3.307551 | 6 | 0.7693728 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0511881 | 0.0636362 | 0.457698 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001125 | 0 | TRUE | 0.3150806 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
